Title: Principal Investigator E-mail: liud@wh.iov.cn


09/2000 - 07/2005; Center for Bioinformatics, College of Life Sciences, Peking University, Beijing;achieved Ph. D. degree in Bioinformatics
09/1996 - 07/2000; Department of Physiology and Biophysics, College of Life Sciences, Peking University, Beijing; achieved B. Sc. Degree

Research Interests

Microbial genomic and meta-genomic analyses

Bioinformatics analyses on pathogenic microbes

Database and applications for DNA barcode

Biological database and software development


S Meng, M Luo, H Sun, X Yu, M Shen, Q Zhang, R Zhou, X Ju, W Tao, D Liu*, H Deng* and Z Lu*. (2010) Identification and characterization of Bmi-1 responding element within the human p16 promoter. Journal of Biological Chemistry, epub of ahead. (*, corresponding author)

Y Ma, Y Feng, D Liu and GF Gao. (2009) Avian influenza virus, Streptococcus suis serotype 2, SARS-coronavirus and beyond: Molecular epidemiology, ecology and the situation in China. Philosophical Transactions of the Royal Society B (Biological Sciences), 364: 2725-2737.

X Song, Y Huang, H Xiao, D Liu and GF Gao. (2009) Stable Non-synonymous Substitutions on NS Gene (NS1 and NS2 proteins) of Qinghai Lake H5N1 Influenza Virus (Clade 2.2) after Successive Passages in Muscovy Ducks, Science in China Series C: Life Science, 52(9): 847-853.

D Liu, X Liu, J Yan, W Liu and GF Gao. (2009) Interspecies transmission and host restriction of avian H5N1 influenza virus. Science in China Series C: Life Science, 52 (5): 428-438.

D Liu, Q Liu, L Wu, B Liu, J Wu, Y Lao, X Li, GF Gao and J Ma*. (2009) Website for avian flu information and bioinformatics. Science in China Series C: Life Science, 52 (5): 470-473

X Song, H Xiao, Y Huang, G Fu, B Jiang, Y Kitamura, W Liu, D Liu and GF Gao. (2009) Serological Surveillance of Influenza A Virus Infection in Swine Populations in Fujian Province, China: No Evidence of Naturally Occurring H5N1 Infection in Pigs. Zoonoses and Public Health, in press.

Z Zhou, X Jiang, D Liu, Z Fan, X Hu, J Yan, M Wang and GF Gao. (2009) Autophagy is involved in influenza A virus replication. Autophagy, in press.

C Wang, M Li, Y Feng, F Zheng, Y Dong, X Pan, G Cheng, R Dong, D Hu, X Feng, J Ge, D Liu, J Wang, M Cao, F Hu and J Tang. (2009) The involvement of sortase A in high virulence of STSS-causing Streptococcus suis serotype 2. Arch Microbiol, 191(1): 23-33.

Y Feng, T Zhao, T Nguyen, K Inui, Y Ma, TH Nguyen, VC Nguyen, D Liu, QA Bui, LT To, C Wang, K Tian and GF Gao. (2008) Porcine Respiratory and Reproductive Syndrome Virus Variants, Vietnam and China, 2007. Emerging Infect Dis, 14(11): 1774-1776.

G Wang, D Zhan, L Li, F Lei, B Liu, D Liu, H Xiao, Y Feng, J Li, B Yang, Z Yin, X Song, X Zhu, Y Cong, Pu, J Wang, J Liu, G F Gao, and Q Zhu. (2008) H5N1 avian influenza re-emergence of Lake Qinghai: phylogenetic and antigenic analyses of the newly isolated viruses and roles of migratory birds in virus circulation. J Gen Virol, 89: 697 - 702.

M Li, X Jiang, D Liu, Y Na, GF Gao and Z Xi. (2008) Autophagy protects LNCaP cells under androgen deprivation conditions. Autophagy, 4(1): 54 – 60.

K Tian, X Yu, T Zhao, Y Feng, Z Cao, C Wang, Y Hu, X Chen, D Hu, X Tian, D Liu, S Zhang, X Deng, Y Ding, L Yang, Y Zhang, H Xiao, M Qiao, B Wang, L Hou, X Wang, X Yang, L Kang, M Sun, P Jin, S Wang, Y Kitamura, J Yan, G F Gao. (2007) Emergence of Fatal PRRSV Variants: Unparalleled Outbreaks of Atypical PRRS in China and Molecular Dissection of the Unique Hallmark. PLoS ONE, 2(6):e526

H Xiao, J Yan, G Wang, D Liu, Y Sun, GF Gao (2007) Recent Progres s in Avian Influenza Research: Role of Migratory Birds and Contributions of the Reverse Genetics Technique. Frontier Science, 1: 62-73. (in Chinese)

C Chen, J Tang, W Dong, C Wang, Y Feng, J Wang, F Zheng, X Pan, D Liu, M Li, Y Song, X Zhu, H Sun, T Feng, Z Guo, A Ju, J Ge, Y Dong, W Sun, Y Jiang, J Wang, J Yan, H Yang, X Wang, G F Gao, R Yang, J Wang, and J Yu. (2007) A Glimpse of Streptococcal Toxic Shock Syndrome from comparative Genomics of S. suis 2 Chinese Isolates. PLoS ONE, 2(3):e315.

Y Feng, F Zheng, X Pan, W Sun, C Wang, Y Dong, A Ju, J Ge, D Liu, C Liu, J Yan, J Tang, G F Gao. (2007) Existence and characterization of allelic variants of Sao, a newly identified surface protein from Streptococcus suis. FEMS Lett, 275(1):80-88.

D Liu, W Gong, Y Bai, J Luo, and Y Zhu. (2005) OsHT, a Rice Gene Encoding for a Plasma-Membrane Localized Histidine Transporter. J Integr Plant Biol, 47(1):92-9

J Feng, D Liu, Y Pan, W Gong, L Ma, J Luo, X W Deng, and Y Zhu. (2005) An annotation update via cDNA sequence analysis and comprehensive profiling of developmental, hormonal or environmental responsiveness of the Arabidopsis AP2/EREBP transcription factor gene family. Plant Mol Biol, 59(6):853-68.

Guo A, He K, Liu D, S Bai, X Gu, L Wei, and J Luo. (2005) DATF: a database of Arabidopsis transcription factors. Bioinformatics, 21(10):2568-9.

S Ji, Y Lu, J Feng, G Wei, J Li, Y Shi, Q Fu, D Liu, J Luo, Y Zhu. (2003) Isolation and analyses of genes preferentially expressed during early cotton fiber development by subtractive PCR and cDNA array. Nucleic Acids Res, 31(10):2534-43.

Fang G, Y Chen, G Gao, D Liu, K He, X Wu, X Gu, and J Luo (2003) Introduction to genome databases. Heredity, 25(4):440-4.

Liu X, Liu D, J Qi, and W Zheng (2002) Simplified amino acid alphabets based on deviation of conditional probability from random background. Phys Rev E Stat Nonlin Soft Matter Phys, 66(2 Pt 1):021906.

G Gao, P Yu, D Liu, K He, X Wu and J Luo. (2002) BiDMAP - A Biological Data Management and Analysis Platform. Computer Engineering, 28:145-153.